Work Location: Middlesex County, Massachusetts

Summary:

Seeking a Research Associate to provide hands-on support for preclinical research activities, focusing on both LNP and antibody-oligonucleotide conjugate platforms. This role involves supporting in vivo studies, processing biological samples, and contributing to bioanalytical assay execution and method development.

Responsibilities:

• Assist with in vivo studies, including preparation for sample collection, tissue dissection, weighing, and organized storage of samples for analysis.
• Manage biological samples throughout their lifecycle, including maintaining freezer logs, updating sample manifests, and coordinating sample transfers between teams.
• Process biological samples by performing tissue disruption, homogenization, and extraction of nucleic acids and proteins from various tissues and plasma.
• Prepare samples for downstream bioanalytical assays such as qPCR/RT-qPCR, ELISA, MSD, and LC-MS/MS, ensuring proper chain of custody and sample integrity.
• Execute routine bioanalytical assays under supervision, with opportunities to develop skills for independent assay execution and method development.
• Maintain accurate and comprehensive records of sample workflows and experimental data using electronic lab notebooks to ensure data integrity and traceability.
• Organize and prepare data, clearly communicating results to relevant stakeholders.
• Support cross-functional collaboration by facilitating sample handoffs and maintaining clear documentation throughout the research process.

Qualifications:

• Bachelor's degree in biomedical sciences, molecular biology, biochemistry, analytical chemistry, or a related field.
• 0–1 years of relevant laboratory experience.
• Willingness to learn rodent and non-human primate tissue handling, dissection, and necropsy support.
• General wet-lab experience, including handling biological samples such as plasma, tissues, or cells.
• Familiarity with bioanalytical techniques (qPCR, ELISA, MSD, LC-MS/MS) is a plus but not required.
• Strong attention to detail, organizational skills, and documentation practices, especially regarding sample tracking and accurate recording of data.
• Ability to maintain sample manifests and ensure accurate recording of tissue weights.
• Commitment to core values such as respect, integrity, excellence, and impact.

Published Category: Discovery Research & Preclinical