Work Location: Middlesex County, Massachusetts

Summary:

Seeking an experienced scientist to independently design, execute, and analyze in vivo rodent studies, mentor junior staff, and contribute to cross-functional research teams. This role requires expertise in animal models, flow cytometry, immunoassays, and strong organizational and communication skills.

Responsibilities:

• Independently design and plan in vivo rodent studies, including endpoints, group sizing, and statistical considerations in collaboration with project leads.
• Serve as the primary in vivo point of contact for assigned projects, managing workstreams from start to finish.
• Execute and coordinate in vivo studies, ensuring animal welfare, accurate dosing, blood collection, clinical observations, and tissue harvesting.
• Conduct and analyze flow cytometry experiments, troubleshoot panels and gating strategies, and interpret data using FlowJo.
• Harvest, process, and preserve biological samples for downstream analysis, and troubleshoot ELISA, MSD, and other immunoassays.
• Mentor and review the work of junior research associates, providing guidance on experimental plans and data analysis.
• Present study results to cross-functional teams and actively participate in research strategy discussions.
• Maintain precise and up-to-date study records within the laboratory information management system.

Qualifications:

• Bachelor’s or Master’s degree in Biology, Pharmacology, Animal Science, or a related Life Sciences field.
• 5–10 years of in vivo biology experience in a biotech or pharmaceutical environment.
• Proven ability to independently design rodent studies and manage workstreams end-to-end.
• Hands-on experience with rodent models and a strong commitment to animal welfare.
• Proficiency in routine dosing methods (IV, SC, IP) and necropsy procedures.
• Comprehensive experience with ex vivo flow cytometry, including tissue collection, sample preparation, staining, acquisition, and FlowJo analysis.
• Expertise in tissue collection and downstream sample processing, including ELISA, MSD, and other immunoassays, with troubleshooting skills.
• Strong organizational skills, attention to detail, and critical thinking; ability to collaborate with principal investigators and proactively address capacity or timeline issues.
• Experience mentoring junior scientists and presenting results to cross-functional teams.
• Ability to thrive in a collaborative, fast-paced, cross-disciplinary environment.
• Proficiency in Microsoft Office (Excel, Word, PowerPoint) and excellent written and oral communication skills.

Published Category: Discovery Research & Preclinical