Details:

  • Compensation: $60 - $77/hour
  • Benefits: Medical, Dental, Vision
  • Employment Classification: Contract To Hire
  • Status: On-Site
  • Job ID: 21816
Scientist I/II, LNP Formulations

Job Title: Scientist I/II, LNP Formulations

Work Location: Middlesex County, Massachusetts

Summary:

Seeking a Scientist I/II specializing in Lipid Nanoparticle (LNP) Formulations to lead the design, execution, and analysis of experiments for next-generation LNP systems. This role focuses on developing, optimizing, and characterizing LNPs for nucleic acid delivery in a dynamic research setting.

Responsibilities:

  • Design and analyze experiments using DOE approaches to create and optimize innovative LNP formulations.
  • Drive formulation innovation by selecting lipids, optimizing compositions, and evaluating process parameters.
  • Conduct LNP screening and characterization, assessing size, PDI, encapsulation efficiency, stability, and performance.
  • Utilize analytical and statistical methods to interpret complex data and inform formulation strategies.
  • Collaborate with multidisciplinary teams to advance research and development programs.
  • Document experiments thoroughly and communicate findings and recommendations to stakeholders.
  • Troubleshoot formulation issues and enhance experimental workflows for continuous improvement.
  • Support scale-up processes and technology transfer activities as required.

Qualifications:

  • PhD or MS in Chemistry, Pharmaceutical Sciences, Chemical Engineering, Materials Science, or a related discipline.
  • Hands-on experience with LNP formulation development and optimization.
  • Expertise in DOE methodologies and statistical experimental design.
  • Proficiency in LNP screening and analytical techniques such as DLS, encapsulation assays, stability studies, and physicochemical characterization.
  • Strong understanding of lipid-based delivery systems and formulation science.
  • Demonstrated ability to work effectively in a fast-paced, team-oriented environment.
  • Excellent problem-solving skills and capability to manage multiple priorities.
  • Effective communication skills for presenting data and influencing technical decisions.

Published Category: Discovery Research & Preclinical

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