Job Title: Principal Investigator, Vaccine Clinical Trials

Work Location: St. Louis County, Missouri

Summary:

Seeking a physician to provide medical oversight and leadership for vaccine clinical trials. This role involves ensuring participant safety, compliance with protocols and regulations, and collaboration with the clinical research team. The position is available on a part-time or full-time basis and requires prior clinical research experience.

Responsibilities:

• Lead and oversee vaccine clinical trials as the Principal Investigator, ensuring adherence to study protocols and regulatory standards.
• Provide comprehensive medical and scientific oversight throughout all phases of study conduct.
• Assess participant eligibility, review medical histories, and evaluate laboratory results and adverse events.
• Manage and document adverse events and serious adverse events, ensuring participant safety at all times.
• Supervise and delegate tasks to clinical research coordinators and other study staff, maintaining high standards of study conduct.
• Review and sign study-related documentation within required timelines to ensure regulatory compliance.
• Participate in meetings, monitoring visits, and regulatory activities as needed, collaborating with research personnel and external partners.
• Maintain accurate documentation and ensure the study site is inspection-ready at all times.

Qualifications:

• MD or DO with an active, unrestricted medical license.
• Board certification or eligibility in Internal Medicine, Family Medicine, or Emergency Medicine preferred.
• Previous clinical research experience required.
• Experience with vaccine trials preferred.
• Familiarity with Good Clinical Practice (GCP) and clinical trial regulations.
• Strong understanding of patient safety and investigator responsibilities.
• Ability to work collaboratively with clinical research staff and external partners.
• Availability to work part-time and start quickly.
• Experience as a Principal Investigator or Sub-Investigator and with interventional clinical trials highly desirable.
• Background in vaccine, infectious disease, or related studies is a plus.

Published Category: Clinical Research