Job Title: Research Scientist II (Chromatography)

Work Location: Middlesex County, Massachusetts

Summary:

Seeking an analytical chemist with expertise in chromatographic analyses and mass spectral data interpretation for complex samples. The role involves supporting diverse projects, including chemical risk assessments, polymer analysis, and impurity screening, while providing technical guidance and method development for chromatography operations.

Responsibilities:

• Independently analyze and interpret complex chromatographic and mass spectral data for a variety of sample types.
• Develop, optimize, and troubleshoot chromatography methods for GC and LC techniques, including column selection and gradient optimization.
• Coordinate and validate analytical activities across multiple instruments, including GCMS and LCMS systems.
• Review, process, and report analytical data using specialized software, ensuring accuracy and timely delivery of results.
• Provide technical support and guidance to team members on instrumentation, troubleshooting, and analytical challenges.
• Contribute to the improvement and development of chromatography protocols and analytical approaches.
• Serve as a subject matter expert for select projects and support client requests related to chromatography.
• Implement quality, workflow, and preventive maintenance strategies for chromatography operations.

Qualifications:

• B.Sc. or M.Sc. in Analytical Chemistry, Chemistry, Chemical Engineering, or equivalent work experience.
• Minimum of 5 years of relevant experience in chromatographic analysis, including LCMS and GCMS.
• Proven ability to develop, optimize, and validate chromatography methods.
• Experience managing or coordinating analytical instrumentation and supporting analytical personnel.
• Proficiency in interpreting accurate mass data, isotopic distributions, adduct formation, monoisotopic mass determination, elemental formula generation, and MS/MS fragmentation patterns for LCMS.
• Expertise in chromatographic retention behavior, EI fragmentation patterns, and mass spectral library matching for GCMS.
• Experience with specialized software (e.g., MassHunter) and Agilent instrumentation is highly desirable.
• Background in one or more of the following environments is a plus: contract R&D, CRO/CDMO, E&L or chemical characterization labs, polymer analysis, failure analysis, environmental labs, manufacturing QC, academic analytical labs, or pharma/startup analytical labs.
• Experience in medical device analysis is beneficial.

Published Category: Analytical & Process Development